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Mouse Anti-Porcine 4-Hydroxyphenylpyruvate Dioxygenase (HPD) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for 4-hydroxyphenylpyruvate dioxygenase. It is affinity purified by protein A. It can be applied to WB, IHC and ELISA assays of 4-hydroxyphenylpyruvate dioxygenase.
Specifications
Target Information
Porcine 4-Hydroxyphenylpyruvate Dioxygenase (pHPPD) is an enzyme that plays a critical role in the tyrosine catabolic pathway in pigs. This enzyme is responsible for the conversion of 4-hydroxyphenylpyruvate (HPP) to homogentisate, a reaction that involves the incorporation of molecular oxygen and the subsequent degradation of homogentisate to fumarate and acetoacetate. pHPPD is a member of the non-heme iron-dependent dioxygenase family, which means it requires an iron ion for its catalytic activity. The enzyme's function is essential for maintaining tyrosine homeostasis and preventing the accumulation of its metabolites, which can be toxic.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Raspail, Corinne, et al. "4-hydroxyphenylpyruvate dioxygenase catalysis: identification of catalytic residues and production of a hydroxylated intermediate shared with a structurally unrelated enzyme." Journal of Biological Chemistry 286.29 (2011): 26061-26070.