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Mouse Anti-Feline CD4 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for feline CD4. It can be applied to FCM, IHC and IP assays of feline CD4.
Specifications
Target Information
Feline CD4 is a cell surface glycoprotein that serves as a co-receptor on the surface of T-helper cells within the feline immune system. It is crucial for the proper functioning of these cells, which play a central role in the adaptive immune response. fCD4 aids in the interaction between the T cell receptor (TCR) and the major histocompatibility complex class II (MHC II) molecules on antigen-presenting cells (APCs). This interaction is essential for the activation of T-helper cells, leading to the initiation of downstream signaling pathways that result in T cell proliferation, differentiation, and production of cytokines.
Shipping and Storage
This product is shipped with ice gel packs. Store at 2°C - 8°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Murphy, Brian, et al. "FIV establishes a latent infection in feline peripheral blood CD4+ T lymphocytes in vivo during the asymptomatic phase of infection." Retrovirology 9 (2012): 1-17.