Mouse Anti-Canine Pepdase (PEPD) Monoclonal Antibody

Canine peptidase is a collective term for enzymes that cleave peptide bonds in peptides and proteins, playing crucial roles in various physiological processes including digestion, immune response, and cellular signaling. In dogs, these peptidases are involved in the metabolism of proteins and regulation of biologically active peptides. They belong to different families, such as the papain-like peptidases, which include cysteine cathepsins involved in intracellular catabolism, angiogenesis, neurogenesis, and tumor growth. Specific peptidases like Kallikrein-related Peptidase 5 (KLK5) are important modulators of skin homeostasis and have been studied in canine cutaneous squamous cell carcinoma, suggesting their potential as molecular biomarkers for predicting prognosis in dogs.