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Mouse Anti-Porcine Casein Kinase 2 Subunit Beta (CSNK2B) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for casein kinase 2 subunit beta. It is affinity purified by protein G. It can be applied to WB, IF, IHC and ELISA assays of casein kinase 2 subunit beta.
Specifications
Target Information
Porcine casein kinase 2 subunit beta (CSNK2B) is a component of the casein kinase 2 (CK2) enzyme, a serine/threonine protein kinase that is highly conserved across eukaryotes. CK2 is known for its broad substrate specificity and is involved in a multitude of cellular processes, including cell growth, proliferation, and the regulation of gene expression. The beta subunit plays a critical role in the stability and activity of the CK2 holoenzyme. As a molecular target, CSNK2B is significant due to the essential functions of CK2 in cellular regulation. Dysregulation of CK2 activity has been implicated in various diseases, particularly in cancer, where it can contribute to uncontrolled cell growth and resistance to apoptosis. Additionally, CK2 has been associated with neurodegenerative diseases and inflammatory conditions due to its role in signal transduction pathways.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Gao, Yuan, et al. "Casein kinase 2 is activated and essential for Wnt/β-catenin signaling." Journal of Biological Chemistry 281.27 (2006): 18394-18400.