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Mouse Anti-Porcine Cartilage Oligomeric Matrix Protein (COMP) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for cartilage oligomeric matrix protein. It is affinity purified by protein G. It can be applied to WB, IF and ELISA assays of cartilage oligomeric matrix protein.
Specifications
Target Information
Porcine cartilage oligomeric matrix protein (COMP), also known as thrombospondin-5, is a large, multi-domain extracellular matrix protein that is abundant in cartilage and other connective tissues. COMP plays a crucial role in the structural integrity of cartilage, contributing to its resistance to compression and tensile forces. It interacts with various components of the extracellular matrix, including collagen and proteoglycans, and is involved in the regulation of chondrocyte function. As a molecular target, COMP is significant due to its association with cartilage homeostasis and its potential role in the pathogenesis of osteoarthritis and other joint diseases. Changes in COMP expression or structure have been observed in conditions characterized by cartilage degradation, making it a potential biomarker and therapeutic target for these diseases.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Cui, Jiarui, et al. "Cartilage oligomeric matrix protein, diseases, and therapeutic opportunities." International journal of molecular sciences 23.16 (2022): 9253.