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Mouse Anti-Chicken β2 Microglobulin Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for chicken β2 microglobulin. It can be applied to FCM, WB and IP assays of chicken β5 microglobulin.
Specifications
Target Information
Chicken β2-Microglobulin (β2M) is a small protein component that is universally expressed in the body and plays a critical role in the immune system of chickens. It is a part of the major histocompatibility complex (MHC) class I molecules, which are essential for the immune response by presenting endogenous antigens to CD8+ T cells. As an invariant chain, β2M associates with the heavy chain of MHC class I molecules, aiding in their transport to the cell surface. This presentation is crucial for the activation of cytotoxic T lymphocytes, which are responsible for identifying and eliminating cells infected with intracellular pathogens or damaged cells.
Shipping and Storage
This product is shipped with ice gel packs. Store at 2°C - 8°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Stoppini, Monica, et al. "Systemic amyloidosis: lessons from β2-microglobulin." Journal of Biological Chemistry 290.16 (2015): 9951-9958.