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Mouse Anti-Porcine Cytochrome P450 3A (CYP3A4) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for cytochrome p450 3A. It is affinity purified by protein A. It can be applied to WB, IF/ICC, IF-P, IHC and ELISA assays of cytochrome p450 3A.
Specifications
Target Information
Porcine cytochrome P450 3A (CYP3A) is a crucial member of the cytochrome P450 enzyme superfamily in pigs, playing a significant role in the metabolism of endogenous and exogenous substances, including drugs and xenobiotics. CYP3A enzymes are responsible for the biotransformation of a vast array of chemicals, making them vital for detoxification processes and the maintenance of physiological homeostasis. This enzyme is highly expressed in the liver and intestine, where it contributes to the first-pass metabolism of orally administered drugs, thus influencing their bioavailability and efficacy. CYP3A is also involved in the synthesis of cholesterol and steroid hormones, highlighting its importance in various metabolic pathways.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Klyushova, Lyubov S., et al. "The role of CYP3A in health and disease." Biomedicines 10.11 (2022): 2686.