Mouse Anti-Porcine Tumor Necrosis Factor Receptor Superfamily Member 1A (TNFR1) Monoclonal Antibody

Porcine tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), also known as the p55 tumor necrosis factor receptor or CD120a, is a crucial component of the immune system in pigs. This receptor plays a significant role in regulating immune responses, particularly in the mediation of inflammation and the regulation of cell survival and apoptosis. TNFRSF1A is expressed on the surface of various cell types, including immune cells, and binds to its ligand, tumor necrosis factor alpha (TNF-α), to initiate intracellular signaling pathways. This interaction is essential for the activation of immune cells, the promotion of inflammation, and the regulation of cell death, which are critical for the host's defense against infections and the maintenance of immune homeostasis.