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Rabbit Anti-Chicken PI 3-Kinase Alpha/Gamma Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for chicken PI 3-kinase alpha/gamma. It can be applied to WB, IHC, IF and ELISA assays of chicken PI 3-kinase alpha/gamma.
Specifications
Target Information
The phosphatidylinositol 3-kinase regulatory subunit (PIK3R1), also known as p85, is a crucial regulatory component of the phosphoinositide 3-kinase (PI3K) pathway. PIK3R1 functions as an adaptor protein that binds to the p110 catalytic subunit of PI3K, stabilizing the enzyme and modulating its activity in response to various cellular signals. This regulatory subunit plays a vital role in multiple cellular processes, including cell growth, differentiation, metabolism, and survival. PIK3R1 is involved in the metabolic actions of insulin and is implicated in the pathogenesis of various diseases, such as cancer and immune disorders. Its expression and activity are tightly regulated through post-translational modifications like phosphorylation and ubiquitination.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Uttamsingh, Shailaja, et al. "Matrix-independent activation of phosphatidylinositol 3-kinase, Stat3, and cyclin A-associated Cdk2 Is essential for anchorage-independent growth of v-Ros-transformed chicken embryo fibroblasts." Journal of Biological Chemistry 278.21 (2003): 18798-18810.