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Rabbit Anti-Canine Interleukin 12B (IL12B) Polyclonal Antibody

Cat. No.VD12N121

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for canine interleukin 12B. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of canine interleukin 12B.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone F11N5
Host Rabbit
Target Species Canine
Species Reactivity Canine
Specificity Canine Interleukin 12B
Immunogen Recombinant protein of interleukin 12B
Purification Protein A Purified
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Canine interleukin 12B (IL-12B) is a key subunit of the IL-12 cytokine, essential for immune regulation. It forms a heterodimer with IL-12A (p35) to create the biologically active IL-12 (p70) complex, which promotes Th1 cell differentiation and enhances the cytotoxic activity of T cells and natural killer cells. IL-12B (p40) can also form IL-23 when paired with the p19 subunit, contributing to immune responses. This cytokine is crucial for sustaining memory/effector Th1 cells and has potential applications in immunotherapy and autoimmune disease research.

Target Canine Interleukin 12B
Target Synonym IL12B
Gene ID 403976
UniProt ID Q28268

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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