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Mouse Anti-Bovine Heterogeneous Nuclear Ribonucleoprotein U (hnRNP U) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for bovine heterogeneous nuclear ribonucleoprotein U. It can be applied to WB assay of bovine heterogeneous nuclear ribonucleoprotein U.
Specifications
Target Information
Heterogeneous nuclear ribonucleoprotein U (hnRNP U), also known as SYNCRIP or Apg-2, is a multifunctional protein that plays a pivotal role in the regulation of gene expression. It is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, which is involved in the processing of pre-mRNA in the nucleus. hnRNP U is known for its ability to bind to specific RNA sequences, influencing mRNA splicing, export, stability, and translation. Its interaction with RNA is crucial for the proper functioning of the cell, as it helps determine which genes are expressed and when. This protein has been implicated in various cellular processes, including cell cycle regulation, apoptosis, and the stress response. Moreover, hnRNP U has been linked to several diseases, such as cancer, where its dysregulation can lead to abnormal gene expression patterns that contribute to tumorigenesis.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Hegde, Muralidhar L., et al. "Enhancement of NEIL1 protein-initiated oxidized DNA base excision repair by heterogeneous nuclear ribonucleoprotein U (hnRNP-U) via direct interaction." Journal of Biological Chemistry 287.41 (2012): 34202-34211.