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Mouse Anti-Bovine Heterogeneous Nuclear Ribonucleoprotein U (hnRNP U) Monoclonal Antibody

Cat. No.VD8N84

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for bovine heterogeneous nuclear ribonucleoprotein U. It can be applied to WB assay of bovine heterogeneous nuclear ribonucleoprotein U.

Specifications

Application WB
Clonality Monoclonal
Classification Primary Antibody
Clone G3N48
Host Mouse
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine Heterogeneous Nuclear Ribonucleoprotein U
Isotype IgG
Immunogen Purified recombinant bovine heterogeneous nuclear ribonucleoprotein U protein fragments
Concentration 1 mg/mL
Conjugation Unconjugated
Physical State Liquid

Target Information

Heterogeneous nuclear ribonucleoprotein U (hnRNP U), also known as SYNCRIP or Apg-2, is a multifunctional protein that plays a pivotal role in the regulation of gene expression. It is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, which is involved in the processing of pre-mRNA in the nucleus. hnRNP U is known for its ability to bind to specific RNA sequences, influencing mRNA splicing, export, stability, and translation. Its interaction with RNA is crucial for the proper functioning of the cell, as it helps determine which genes are expressed and when. This protein has been implicated in various cellular processes, including cell cycle regulation, apoptosis, and the stress response. Moreover, hnRNP U has been linked to several diseases, such as cancer, where its dysregulation can lead to abnormal gene expression patterns that contribute to tumorigenesis.

Target Bovine Heterogeneous Nuclear Ribonucleoprotein U
Target Synonym HNRNPU; HNRPU
Gene ID 539950
UniProt ID A2VDN7

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Hegde, Muralidhar L., et al. "Enhancement of NEIL1 protein-initiated oxidized DNA base excision repair by heterogeneous nuclear ribonucleoprotein U (hnRNP-U) via direct interaction." Journal of Biological Chemistry 287.41 (2012): 34202-34211.
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