Mouse Anti-Porcine Dipeptidyl-Peptidase 4 (DPP4) Monoclonal Antibody

Porcine dipeptidyl-peptidase 4 (DPP4), also known as CD26, is a widely expressed serine protease that plays a crucial role in the regulation of various biological processes, including immune cell activation, glucose homeostasis, and the processing of peptide hormones. DPP4 is particularly known for its ability to inactivate certain incretin hormones, such as glucagon-like peptide-1 (GLP-1), which are important in the regulation of insulin secretion. As a molecular target, DPP4 is significant due to its role in metabolic and immune functions. It has been implicated in the pathogenesis of type 2 diabetes, where its inhibition can lead to increased levels of active incretins and improved glycemic control. Additionally, DPP4 has been associated with inflammatory diseases and cancer, making it a potential therapeutic target in these conditions as well.