This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Anti-Porcine Neurofilament Light Polypeptide (NF-L) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for neurofilament light polypeptide. It is affinity purified by protein A. It can be applied to WB, IF, IHC, ELISA and FC assays of neurofilament light polypeptide.
Specifications
Target Information
Porcine Neurofilament Light Polypeptide (pNF-L) is a vital component of the neuronal cytoskeleton, playing a critical role in the structure and function of nerve cells. This protein is expressed predominantly in neurons and is a key determinant of axonal caliber, contributing to the maintenance of neuronal integrity and the efficient transmission of nerve impulses. pNF-L is part of the neurofilament triplet proteins, which include light, medium, and heavy chains. These proteins form a dynamic network within axons, providing structural support and playing a role in the regulation of axonal transport. The phosphorylation state of pNF-L can modulate its function, affecting neuronal health and the response to injury.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Carter, Julie, et al. "Neurofilament (NF) assembly; divergent characteristics of human and rodent NF-L subunits." Journal of Biological Chemistry 273.9 (1998): 5101-5108.