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Mouse Anti-Canine Melan A Monoclonal Antibody

Cat. No.VD11N213

Product TypeAnimal-targeted Antibodies

Size 100 μg

Product Overview

BioVenic mouse monoclonal antibody is specific for canine melan A. It can be applied to WB, ICC/IF, IHC and FACS assays of canine melan A.

Specifications

Application WB; ICC/IF; IHC; FACS
Clonality Monoclonal
Classification Primary Antibody
Clone S18N12
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Melan A
Isotype IgG1
Immunogen Recombinant protein of melan A
Concentration 0.2 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Sodium Azide
Buffer Phosphate Buffered Saline, 0.05% BSA
Physical State Liquid

Target Information

Canine melan A, also known as MART-1, is a melanocytic marker that is used in immunohistochemical testing to differentiate canine extramedullary plasmacytomas (CEMPs) from other round cell tumors, including lymphoma, cutaneous histiocytoma, and amelanotic melanomas. It is expressed in melanocytes and melanoma cells, making it a valuable tool for the diagnosis of melanocytic neoplasms in dogs. Melan A is part of a larger immunopanel that includes λ light chain, CD20, and PNL2, which aids in distinguishing CEMPs from amelanotic melanomas. Its expression is also utilized in the characterization of primary cultures of normal and neoplastic canine melanocytes, contributing to the understanding of canine melanoma as a model for human disease.

Target Canine Melan A
Target Synonym MLANA
Gene ID 403495
UniProt ID A0A8I3PEY8

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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