Mouse Anti-Porcine IgM μ Chain Specific Monoclonal Antibody

Porcine IgM μ chain is a crucial component of the immune system in pigs, playing a significant role in the primary immune response. It is characterized by its high molecular weight and a pentameric structure, consisting of five subunits and a single J-chain. Each subunit comprises a pair of heavy (μ) and light chains, with the heavy chain containing one variable and four constant regions. IgM is often referred to as a macroglobulin due to its large size and is the first antibody to be produced in response to an initial exposure to an antigen. It is particularly effective at activating the complement system, a critical part of the immune response that helps to clear pathogens. The μ chain of porcine IgM is also significant in the context of vaccine development and understanding disease resistance in pigs.