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Mouse Anti-Canine NQO1 Monoclonal Antibody

Cat. No.VD11N19

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine NQO1. It can be applied to WB, ICC/IF, IHC, FACS and IP assays of canine NQO1.

Specifications

Application WB; ICC/IF; IHC; FACS; IP
Clonality Monoclonal
Classification Primary Antibody
Clone S9N19
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine NQO1
Isotype IgG1
Immunogen Recombinant protein of NQO1
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Sodium Azide
Buffer Tris-Glycine, 150mM NaCl
Physical State Liquid

Target Information

Canine NQO1, or NAD(P)H:quinone oxidoreductase 1, is a cytosolic 2-electron reductase that plays a vital role in cellular defense against oxidative stress and in redox processes. This enzyme is highly inducible and has the ability to prevent certain quinones from one-electron redox cycling, which can lead to the production of radical species. NQO1 is also involved in the generation of antioxidant forms of ubiquinone and vitamin E, contributing to the plasma membrane redox system. Its expression is often altered in various tumors, and it is associated with conditions like Alzheimer's disease, making it a significant target for therapeutic interventions in canine health.

Target Canine NQO1
Target Synonym Azoreductase; DT-diaphorase; Menadione reductase ; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1
Gene ID 610935
UniProt ID A0A8I3NAN7

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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