Mouse Anti-Porcine Nuclear Factor A (NFIA) Monoclonal Antibody

Porcine nuclear factor I/A (NFIA) is a transcription factor that plays a crucial role in the development of the central nervous system and other organ systems. It is involved in regulating cell proliferation and differentiation, making it essential for normal brain development. NFIA is also implicated in the development of various cancers, where its deregulation can lead to uncontrolled cell proliferation or failure to differentiate, potentially contributing to tumor growth. In the context of glioma, high expression levels of NFIA are associated with better clinical outcomes, suggesting a role in tumor suppression. Furthermore, NFIA is involved in the transcriptional regulation of genes critical for the brown fat gene program, which is important for thermogenesis and energy expenditure.