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Rabbit Anti-Canine Calcitonin Gene Related Peptide 1 (CGRP1) Polyclonal Antibody-[HRP]
Product Overview
BioVenic rabbit polyclonal antibody is specific for canine calcitonin gene related peptide 1. It is affinity purified by protein G. It can be applied to ELISA assay of canine calcitonin gene related peptide 1.
Specifications
Target Information
Canine calcitonin gene-related peptide 1 (CGRP-1) is a neuropeptide with diverse physiological functions, primarily involved in vasodilation and modulation of sensory nerve activity. It is expressed in sensory neurons and other cell types, such as motor neurons and neuroendocrine cells. CGRP-1 acts through G protein-coupled receptors, particularly the calcitonin receptor-like receptor (CLR) complexed with receptor activity-modifying protein 1 (RAMP1), which is crucial for its vasodilatory effects. In dogs, CGRP-1 has been shown to influence digestive motility by slowing gastric emptying through its action on CGRP-1 receptors. Additionally, it plays a role in cardiovascular regulation, causing vasodilation and affecting heart rate and blood pressure.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.