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Mouse Anti-Canine Ras-Related Protein Rab-2A Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine Ras-related protein Rab-2A. It can be applied to WB, IF and ICC assays of canine Ras-related protein Rab-2A.
Specifications
Target Information
Rab-2A, a member of the RAS oncogene family, is a small GTPase enzyme that is integral to the regulation of vesicular transport within the cell. It plays a pivotal role in the early secretory pathway, specifically in the transport of proteins from the endoplasmic reticulum to the Golgi apparatus. As a molecular switch, RAB2A cycles between an active GTP-bound state and an inactive GDP-bound state, enabling it to recruit and interact with various effector proteins that facilitate the correct sorting and trafficking of vesicles. This precise regulation is critical for maintaining cellular function and homeostasis.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Chen, Zi-Yue, et al. "Rab2A regulates the progression of nonalcoholic fatty liver disease downstream of AMPK-TBC1D1 axis by stabilizing PPARγ." PLoS Biology 20.1 (2022): e3001522.