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Mouse Anti-Canine Ras-Related Protein Rab-2A Monoclonal Antibody

Cat. No.VD8N140

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for canine Ras-related protein Rab-2A. It can be applied to WB, IF and ICC assays of canine Ras-related protein Rab-2A.

Specifications

Application WB; IF; ICC
Clonality Monoclonal
Classification Primary Antibody
Clone G4N3
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Ras-Related Protein Rab-2A
Isotype IgG
Immunogen Purified recombinant canine Ras-related protein Rab-2A (C-terminus) protein fragments
Concentration 1 mg/mL
Conjugation Unconjugated
Physical State Liquid

Target Information

Rab-2A, a member of the RAS oncogene family, is a small GTPase enzyme that is integral to the regulation of vesicular transport within the cell. It plays a pivotal role in the early secretory pathway, specifically in the transport of proteins from the endoplasmic reticulum to the Golgi apparatus. As a molecular switch, RAB2A cycles between an active GTP-bound state and an inactive GDP-bound state, enabling it to recruit and interact with various effector proteins that facilitate the correct sorting and trafficking of vesicles. This precise regulation is critical for maintaining cellular function and homeostasis.

Target Canine Ras-Related Protein Rab-2A
Target Synonym RAB2A
Gene ID 404009
UniProt ID P61105

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Chen, Zi-Yue, et al. "Rab2A regulates the progression of nonalcoholic fatty liver disease downstream of AMPK-TBC1D1 axis by stabilizing PPARγ." PLoS Biology 20.1 (2022): e3001522.
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