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Mouse Anti-Porcine IgA Secretory Component Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for porcine IgA secretory component. It can be applied to ELISA assay of porcine IgA secretory component.
Specifications
Target Information
Porcine IgA secretory component (SC) is a vital part of secretory IgA (sIgA), which is essential for mucosal immunity in pigs. SC is derived from the polymeric immunoglobulin receptor (pIgR) and is responsible for transporting IgA across mucosal epithelial cells. Once transported, the pIgR is cleaved, and SC remains attached to IgA, forming sIgA. This complex protects sIgA from degradation by proteases and enhances its ability to bind pathogens, preventing their adherence to mucosal surfaces. SC also plays a role in neutralizing inflammatory host factors and has been shown to interact with bacterial surface proteins, inhibiting their invasion and adherence to host cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.