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Mouse Anti-Porcine Cullin 4A (CUL4A) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for cullin 4A. It is affinity purified by protein A. It can be applied to WB, IP, IF, IHC and ELISA assays of cullin 4A.
Specifications
Target Information
Porcine cullin 4A (CUL4A) is a component of the cullin-RING ligase (CRL) family of E3 ubiquitin ligases, which play a critical role in the regulation of protein stability and cellular signaling in pigs. CUL4A, along with its binding partners, forms a complex that targets specific proteins for ubiquitination, a process that marks proteins for degradation by the proteasome. This protein is involved in a wide range of cellular processes, including DNA repair, cell cycle control, and transcriptional regulation. The CUL4A-based E3 ligase complex is versatile and can accommodate various substrate adaptors, allowing it to target a broad spectrum of proteins for ubiquitin-mediated degradation.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Shiyanov, Pavel, et al. "Cullin 4A associates with the UV-damaged DNA-binding protein DDB." Journal of Biological Chemistry 274.50 (1999): 35309-35312.