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Mouse Anti-Canine PPME1 Monoclonal Antibody

Cat. No.VD11N85

Product TypeAnimal-targeted Antibodies

Size 100 μL

Product Overview

BioVenic mouse monoclonal antibody is specific for canine PPME1. It can be applied to WB, ICC/IF, IHC and FACS assays of canine PPME1.

Specifications

Application WB; ICC/IF; IHC; FACS
Clonality Monoclonal
Classification Primary Antibody
Clone S13N37
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine PPME1
Isotype IgG1
Immunogen Recombinant protein of PPME1
Concentration 0.96 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol
Physical State Liquid

Target Information

Canine PPME1 (protein phosphatase methylesterase 1) is an enzyme localized to the nucleus that plays a role in regulating the protein phosphatase 2A catalytic subunit, which supports the ERK pathway through the dephosphorylation of regulatory proteins. This gene is expressed ubiquitously, with particularly high levels in testis and brain, and it has been implicated in the progression of malignant glioma. In dogs, PPME1 may serve a similar function, influencing cellular signaling pathways and potentially playing a role in neurological diseases and cancer. Understanding the activity and regulation of PPME1 in dogs is crucial for insights into its role in health and disease, particularly in the context of neurological conditions and oncology.

Target Canine PPME1
Target Synonym Protein phosphatase methylesterase 1
Gene ID 612812
UniProt ID A0A8I3NEY2

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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