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Mouse Anti-Feline CD8 Monoclonal Antibody

Cat. No.VD7N365

Product TypeAnimal-targeted Antibodies

Size 0.5 mg

Product Overview

BioVenic mouse monoclonal antibody is specific for feline CD8. It can be applied to FCM, IP and IHC assays of feline CD8.

Specifications

Application FCM; IHC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone L12N33
Host Mouse
Target Species Feline
Species Reactivity Feline
Specificity Feline CD8β
Isotype IgG1
Immunogen Feline thymocytes
Purity > 90%
Concentration 0.5 mg/mL
Conjugation Unconjugated
Buffer Borate Buffered Saline, pH 8.2
Physical State Liquid

Target Information

Feline CD8 is a surface glycoprotein that acts as a co-receptor on cytotoxic T lymphocytes in cats. It is part of the CD8 complex, which is composed of CD8α and CD8β chains, and plays a pivotal role in the immune response against intracellular pathogens. fCD8 is involved in the recognition of antigens presented by major histocompatibility complex (MHC) class I molecules on the surface of target cells. It enhances the interaction between the T cell receptor (TCR) and MHC class I, leading to the activation of cytotoxic T cells, which then eliminate infected or abnormal cells.

Target Feline CD8β
Target Synonym fCD8
Gene ID 493948
UniProt ID P79355

Shipping and Storage

This product is shipped with ice gel packs. Store at 2°C - 8°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Roche, Sylvain, et al. "Diversity of trends of viremia and T-cell markers in experimental acute feline immunodeficiency virus infection." Plos one 8.2 (2013): e56135.
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