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Mouse Anti-Chicken E-Cadherin Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for e-cadherin. It is affinity purified by protein A. It can be applied to WB, IHC, IF/ICC, IF-P and ELISA assays of e-cadherin.
Specifications
Target Information
Chicken E-cadherin, a homolog of the human E-cadherin, is a vital cell adhesion molecule in avian species that is integral to the structural integrity of epithelial tissues. Found on the cell surface, this glycoprotein facilitates strong cell-cell adhesion through calcium-dependent homophilic interactions, where the E-cadherin molecules on adjacent cells bind to each other, forming adherens junctions. In chickens, E-cadherin plays a critical role in embryonic development, tissue morphogenesis, and the maintenance of tissue homeostasis. It is particularly important in the development of the gastrointestinal tract, where it helps to establish and preserve the epithelial barrier against pathogens and other environmental stressors.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Loh, Chin-Yap, et al. "The E-cadherin and N-cadherin switch in epithelial-to-mesenchymal transition: signaling, therapeutic implications, and challenges." Cells 8.10 (2019): 1118.