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Mouse Anti-Canine Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) Monoclonal Antibody

Cat. No.VD8N127

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for canine peroxisome proliferator-activated receptor gamma. It can be applied to WB, IF and ICC assays of canine peroxisome proliferator-activated receptor gamma.

Specifications

Application WB; IF; ICC
Clonality Monoclonal
Classification Primary Antibody
Clone G3N91
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Peroxisome Proliferator-Activated Receptor Gamma
Isotype IgG
Immunogen Purified recombinant canine peroxisome proliferator-activated receptor gamma (C-terminus) protein fragments
Concentration 1 mg/mL
Conjugation Unconjugated
Physical State Liquid

Target Information

Peroxisome proliferator-activated receptor gamma (PPAR-γ) is a nuclear receptor known for its key role in the regulation of cellular differentiation, metabolism, and inflammation. As a transcription factor, PPAR-γ controls the expression of genes involved in fatty acid storage, glucose metabolism, and insulin sensitivity, making it a critical player in energy homeostasis. PPAR-γ is highly expressed in adipose tissue, where it promotes the differentiation of preadipocytes into adipocytes and regulates lipid metabolism. Its activation can lead to increased fatty acid uptake and storage, as well as the production of anti-inflammatory molecules, contributing to its insulin-sensitizing and anti-inflammatory properties.

Target Canine Peroxisome Proliferator-Activated Receptor Gamma
Target Synonym PPARG; NR1C3
Gene ID 403606
UniProt ID Q4U3Q4

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Wang, Limei, et al. "Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review." Biochemical pharmacology 92.1 (2014): 73-89.
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