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Mouse Anti-Porcine Double PHD Fingers 3 (DPF3) Monoclonal Antibody

Cat. No.VD8N511

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for double PHD fingers 3. It is affinity purified by protein A. It can be applied to WB and ELISA assays of double PHD fingers 3.

Specifications

Application WB; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G11N8
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Double PHD Fingers 3
Isotype IgG2
Immunogen Recombinant protein of double PHD fingers 3
Purification Protein A Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine double PHD fingers 3 (DPF3), also known as Bif-1 or DP-1, is a protein that belongs to the double plant homeodomain (PHD) finger family. These proteins are characterized by the presence of two PHD zinc fingers, which enable them to interact with histone proteins and play a role in chromatin remodeling and gene regulation. DPF3 is involved in various cellular processes, including cell cycle control, DNA damage response, and apoptosis. As a molecular target, DPF3 is significant due to its implications in the regulation of gene expression and its association with cellular stress responses. It has been linked to several diseases, particularly in the context of cancer, where its overexpression or dysregulation can contribute to tumorigenesis and resistance to therapy.

Target Double PHD Fingers 3
Target Synonym BAF45C; BRG1 associated factor 45C
Gene ID 100156555
UniProt ID F1S3L6

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Matsuyama, Reiko, et al. "Double PHD fingers protein DPF2 recognizes acetylated histones and suppresses the function of estrogen-related receptor α through histone deacetylase 1." Journal of Biological Chemistry 285.24 (2010): 18166-18176.
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