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Mouse Anti-Canine MOB1B Monoclonal Antibody

Product Overview

BioVenic mouse monoclonal antibody is specific for canine MOB1B. It can be applied to WB and IHC assays of canine MOB1B.

Specifications

Application WB; IHC

Clonality Monoclonal

Classification Primary Antibody

Clone S13N46

Host Mouse

Target Species Canine

Species Reactivity Canine

Specificity Canine MOB1B

Isotype IgG2

Immunogen Recombinant protein of MOB1B

Concentration 1 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium Azide

Buffer Phosphate Buffered Saline, 1% BSA, 50% Glycerol

Physical State Liquid

Target Information

Canine MOB1B is a crucial component of the Hippo signaling pathway, which is involved in cell proliferation, cell-lineage specification, and mitotic exit in various organisms, including dogs. This protein plays a significant role in activating NDR/LATS1 kinases and is a core part of the Hippo pathway along with MST1/2, LATS1/2, and SAV1. The phosphorylation of MOB1B by MST1/2 kinase is essential for its interaction with NDR/LATS kinases, which in turn phosphorylates YAP and TAZ, inhibiting their activity.

Target Canine MOB1B

Target Synonym MOB kinase activator 1B

Gene ID 482187

UniProt ID A0A8C0NKP8

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.