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Mouse Anti-Canine Sirtuin 2 (SIRT2) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for sirtuin 2. It is affinity purified by protein G. It can be applied to WB, IF, IHC and ELISA assays of sirtuin 2.
Specifications
Target Information
Canine sirtuin 2 (cSIRT2) is a NAD+-dependent deacetylase enzyme that is part of the sirtuin family, known for its regulatory roles in various cellular processes in dogs. cSIRT2 is predominantly found in the cytoplasm and mitochondria, where it exerts its influence on cell cycle regulation, metabolic balance, and stress response. This enzyme is particularly noted for its ability to deacetylate alpha-tubulin, a key component of microtubules. By doing so, cSIRT2 modulates the dynamics and stability of the microtubules, which are essential for maintaining cellular structure and facilitating intracellular transport mechanisms.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Marfè, Gabriella, et al. "Involvement of FOXO transcription factors, TRAIL-FasL/Fas, and sirtuin proteins family in canine coronavirus type II-induced apoptosis." Plos one 6.11 (2011): e27313.