Mouse Anti-Porcine Glutamate Decarboxylase 1 (GAD1) Monoclonal Antibody

Porcine glutamate decarboxylase 1 (GAD1) is an enzyme that is instrumental in the neurotransmitter synthesis within the pig's central nervous system. GAD1 is responsible for the decarboxylation of glutamate, the major excitatory neurotransmitter in the brain, to form gamma-aminobutyric acid (GABA), the principal inhibitory neurotransmitter. This conversion is pivotal for maintaining the balance between excitation and inhibition in neuronal networks, which is essential for proper brain function. GAD1 plays a critical role in the regulation of neuronal activity, and its dysregulation can lead to neurological disorders. It is highly expressed in the brain, particularly in the regions associated with cognition, emotion, and motor control. The enzyme is also subject to various post-translational modifications that can influence its activity and subcellular localization.