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Mouse Anti-Equine Interleukin 10 (IL10) Monoclonal Antibody

Name: Mouse Anti-Equine Interleukin 10 (IL10) Monoclonal Antibody
SKU: VD12N186
Rating: 5 (1 reviews)

Cat. No.VD12N186

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

BioVenic mouse monoclonal antibody is specific for equine interleukin 10. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of equine interleukin 10.

Specifications

Application WB; IHC; IF/ICC

Clonality Monoclonal

Classification Primary Antibody

Clone F13N30

Host Mouse

Target Species Equine

Species Reactivity Equine

Specificity Equine Interleukin 10

Isotype IgG1

Immunogen Recombinant protein of interleukin 10

Purification Protein A Purified

Conjugation Unconjugated

Preservative and Stabilizer 0.05% Proclin 300

Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol

Physical State Liquid

Target Information

Equine interleukin 10 (IL-10) is a pleiotropic cytokine primarily produced by monocytes and lymphocytes, playing a crucial role in immunoregulation and inflammation. It downregulates the expression of pro-inflammatory cytokines and enhances B cell survival and proliferation. IL-10 also blocks NF-κB activity and regulates the JAK-STAT signaling pathway.

Target Equine Interleukin 10

Target Synonym IL10; Cytokine synthesis inhibitory factor; CSIF

Gene ID 100034187

UniProt ID Q28374

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Wise, Lyn M., et al. "Anti-fibrotic actions of equine interleukin-10 on transforming growth factor-beta1-stimulated dermal fibroblasts isolated from limbs of horses." Frontiers in Veterinary Science 7 (2020): 577835.