Mouse Anti-Porcine Flotillin 1 Monoclonal Antibody

Porcine flotillin 1, a vital membrane-associated protein, is widely expressed in mammalian cells and plays a significant role in cellular processes such as signaling, endocytosis, and protein trafficking. It is particularly notable for its involvement in lipid rafts, specialized membrane microdomains rich in cholesterol and sphingolipids, which are crucial for cellular signaling. The protein's function is regulated by post-translational modifications like S-palmitoylation, which influences its membrane association and interaction with other cellular components. In the medical field, Porcine Flotillin 1 has gained attention for its implications in cancer biology; it is often overexpressed in various tumors and is linked with poor prognosis, making it a potential biomarker for cancer diagnosis and a therapeutic target for interventions. Its role in tumorigenesis includes promotion of cell migration, invasion, and its association with oncogenic signaling pathways, highlighting its significance in the advancement and metastasis of cancers.