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Rabbit Anti-Bovine Fibrinogen Beta (FGB) Polyclonal Antibody

Cat. No.VD12N253

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for bovine fibrinogen beta. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of bovine fibrinogen beta.

Specifications

Application WB; IHC; IF/ICC
Clonality Polyclonal
Classification Primary Antibody
Clone F22N4
Host Rabbit
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine Fibrinogen Beta
Immunogen Recombinant protein of fibrinogen beta
Purification Protein A Purified
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Bovine fibrinogen beta (FGB) is a subunit of the fibrinogen molecule, a soluble plasma glycoprotein synthesized in the liver. It plays a critical role in blood clotting by forming fibrin clots upon activation by thrombin. Fibrinogen also regulates the activation of NF-κB in endothelial cells, leading to the upregulation of inflammatory chemokines such as MCP-1 and IL-8. Defects in the FGB gene can cause congenital afibrinogenemia, a disorder characterized by severe bleeding due to the absence or extremely low levels of plasma fibrinogen.

Target Bovine Fibrinogen Beta
Target Synonym FGB
Gene ID 510522
UniProt ID P02676

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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