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Mouse Anti-Bovine Gelsolin (GSN) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for bovine gelsolin. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of bovine gelsolin.
Specifications
Target Information
Bovine gelsolin is a multifunctional actin-binding protein that plays a crucial role in the remodeling of the cytoskeleton, which determines cell shape, chemotaxis, and secretion. It is a Ca2+-dependent lipid binding actin regulatory protein, possessing three different actin modulating activities: severing of F-actin, nucleation of actin polymerization, and capping of filaments barbed end. Gelsolin has three actin binding sites, two high affinity Ca2+ binding sites, and two binding sites for PIP2, making it a key player in cellular functions such as cell movement, morphological changes, metabolism, apoptosis, and phagocytosis.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.