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Mouse Anti-Bovine Gelsolin (GSN) Monoclonal Antibody

Cat. No.VD11N339

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for bovine gelsolin. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of bovine gelsolin.

Specifications

Application WB; IHC; IF/ICC
Clonality Monoclonal
Classification Primary Antibody
Clone D23N11
Host Mouse
Target Species Bovine
Species Reactivity Bovine
Specificity Bovine Gelsolin
Isotype IgG2
Immunogen Recombinant protein of gelsolin
Purification Protein A Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Bovine gelsolin is a multifunctional actin-binding protein that plays a crucial role in the remodeling of the cytoskeleton, which determines cell shape, chemotaxis, and secretion. It is a Ca2+-dependent lipid binding actin regulatory protein, possessing three different actin modulating activities: severing of F-actin, nucleation of actin polymerization, and capping of filaments barbed end. Gelsolin has three actin binding sites, two high affinity Ca2+ binding sites, and two binding sites for PIP2, making it a key player in cellular functions such as cell movement, morphological changes, metabolism, apoptosis, and phagocytosis.

Target Bovine Gelsolin
Target Synonym GSN
Gene ID 535077
UniProt ID Q3SX14

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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