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Mouse Anti-Swine CD3 Monoclonal Antibody
Product Overview
O7H2 monoclonal antibody is specific for Swine CD3, also know as Swine T3E or TCRE. It was purified by affinity chromatography on Protein A from tissue culture supernatant. It can be applied for Flow Cytometry (FC); Immunohistochemical (IHC); Immunoprecipitation (IP) and Western Blot (WB).
Specifications
Target Information
Cluster of differentiation 3 (CD3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+naive T cells) and T helper cells (CD4+ naive T cells). Swine CD3 genes were located in thymus medulla and the T-cell regions of peripheral lymphoid tissues. CD3- T cell receptor (TCR) complex plays a central role in the T-cell-mediated immunoresponse as it is involved in the recognition of antigens and subsequent signal transduction and activation of immunocompetent T lymphocytes in swine.
Shipping and Storage
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt (up to 12 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
References
- Mair, Kerstin H., et al. "Porcine CD3+ NKp46+ lymphocytes have NK-cell characteristics and are present in increased frequencies in the lungs of influenza-infected animals." Frontiers in immunology 7 (2016): 263.