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Mouse Anti-Porcine 3-Hydroxybutyrate Dehydrogenase Type 1 (BDH1) Monoclonal Antibody

Cat. No.VD8N364

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for 3-hydroxybutyrate dehydrogenase type 1. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of 3-hydroxybutyrate dehydrogenase type 1.

Specifications

Application WB; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G8N17
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity 3-Hydroxybutyrate Dehydrogenase Type 1
Isotype IgG1
Immunogen Recombinant protein of 3-hydroxybutyrate dehydrogenase type 1
Purification Protein A Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine 3-hydroxybutyrate dehydrogenase type 1 (pBDH1), also known as 3-hydroxybutyrate dehydrogenase 1 or simply as the rate-limiting enzyme in the breakdown of ketone bodies, plays a crucial role in the metabolism of ketone bodies, which are water-soluble molecules that serve as an alternative energy source for the brain and muscles during periods of fasting, low carbohydrate intake, or high-energy demand. pBDH1 is expressed in tissues such as the liver, heart, and skeletal muscle, where it facilitates the conversion of 3-hydroxybutyrate back to acetyl-CoA, allowing for the utilization of ketone bodies in the citric acid cycle. This enzyme is particularly important in the context of energy homeostasis and has implications for the health and performance of pigs under various nutritional and physiological conditions.

Target 3-Hydroxybutyrate Dehydrogenase Type 1
Target Synonym BDH; BDH1
Gene ID 100511473
UniProt ID F1SQX8

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Xu, Bu-tuo, et al. "Bdh1 overexpression ameliorates hepatic injury by activation of Nrf2 in a MAFLD mouse model." Cell Death Discovery 8.1 (2022): 49.
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