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Mouse Anti-Porcine 3-Hydroxybutyrate Dehydrogenase Type 1 (BDH1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for 3-hydroxybutyrate dehydrogenase type 1. It is affinity purified by protein A. It can be applied to WB, IF, IHC and ELISA assays of 3-hydroxybutyrate dehydrogenase type 1.
Specifications
Target Information
Porcine 3-hydroxybutyrate dehydrogenase type 1 (pBDH1), also known as 3-hydroxybutyrate dehydrogenase 1 or simply as the rate-limiting enzyme in the breakdown of ketone bodies, plays a crucial role in the metabolism of ketone bodies, which are water-soluble molecules that serve as an alternative energy source for the brain and muscles during periods of fasting, low carbohydrate intake, or high-energy demand. pBDH1 is expressed in tissues such as the liver, heart, and skeletal muscle, where it facilitates the conversion of 3-hydroxybutyrate back to acetyl-CoA, allowing for the utilization of ketone bodies in the citric acid cycle. This enzyme is particularly important in the context of energy homeostasis and has implications for the health and performance of pigs under various nutritional and physiological conditions.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Xu, Bu-tuo, et al. "Bdh1 overexpression ameliorates hepatic injury by activation of Nrf2 in a MAFLD mouse model." Cell Death Discovery 8.1 (2022): 49.