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Mouse Anti-Porcine Phosphoglycerate Mutase Family Member 5 (PGAM5) Monoclonal Antibody

Cat. No.VD8N384

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for phosphoglycerate mutase family member 5. It is affinity purified by protein G. It can be applied to WB, IHC and ELISA assays of phosphoglycerate mutase family member 5.

Specifications

Application WB; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G8N37
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Phosphoglycerate Mutase Family Member 5
Isotype IgG1
Immunogen Recombinant protein of phosphoglycerate mutase family member 5
Purification Protein G Purified
Concentration 1000 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine phosphoglycerate mutase family member 5 (pPGAM5), also known as phosphoglycerate mutase 5 or brain glycogen phosphorylase, is an enzyme that plays a significant role in cellular metabolism. pPGAM5 is involved in the conversion of 3-phosphoglycerate to 2-phosphoglycerate, a key step in both glycolysis and gluconeogenesis, the metabolic pathways that break down glucose to produce energy and synthesize glucose from non-carbohydrate sources, respectively. This protein is highly expressed in the brain and skeletal muscle, where it contributes to the regulation of energy metabolism. In pigs, pPGAM5 may be particularly important for supporting the high-energy demands of the brain during periods of cognitive activity and for maintaining muscle function and energy homeostasis.

Target Phosphoglycerate Mutase Family Member 5
Target Synonym BXLBv68; PGAM5
Gene ID 106508765
UniProt ID A0A286ZVG1

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Wilkins, Jordan M., et al. "A conserved motif mediates both multimer formation and allosteric activation of phosphoglycerate mutase 5." Journal of Biological Chemistry 289.36 (2014): 25137-25148.
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