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Mouse Anti-Chicken Major Histocompatibility Complex (MHC) Class II Monoclonal Antibody

Cat. No.VD7N260

Product TypeAnimal-targeted Antibodies

Size 0.5 mg

Product Overview

BioVenic mouse monoclonal antibody is specific for chicken major histocompatibility complex class II. It can be applied to FCM, IHC and IP assays of chicken major histocompatibility complex class II.

Specifications

Application FCM; IHC; IP
Clonality Monoclonal
Classification Primary Antibody
Clone L10N74
Host Mouse
Target Species Chicken
Species Reactivity Chicken; Avian
Specificity Chicken Major Histocompatibility Complex Class II β-Chain
Isotype IgG1
Purity > 90%
Concentration 0.5 mg/mL
Conjugation Unconjugated
Buffer Borate Buffered Saline, pH 8.2
Physical State Liquid

Target Information

Chicken major histocompatibility complex class II molecules are integral membrane glycoproteins that play a central role in the avian immune system. They are expressed primarily on the surface of antigen-presenting cells (APCs) such as macrophages, B lymphocytes, and dendritic cells. cMHC II molecules are crucial for the initiation of T cell-mediated immune responses by presenting antigenic peptides to CD4+ T-helper cells.

Target Chicken Major Histocompatibility Complex Class II β-Chain
Target Synonym B-L
Gene ID 693256; 101747454

Shipping and Storage

This product is shipped with ice gel packs. Store at 2°C - 8°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Wieczorek, Marek, et al. "Major histocompatibility complex (MHC) class I and MHC class II proteins: conformational plasticity in antigen presentation." Frontiers in Immunology 8 (2017): 292.
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