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Mouse Anti-Canine Carbamoyl Phosphate Synthetase 1 (CPS1) Monoclonal Antibody

Cat. No.VD11N261

Product TypeAnimal-targeted Antibodies

Size 100 μg

Product Overview

BioVenic mouse monoclonal antibody is specific for canine carbamoyl phosphate synthetase 1. It can be applied to ICC/IF and IHC assays of canine carbamoyl phosphate synthetase 1.

Specifications

Application ICC/IF; IHC
Clonality Monoclonal
Classification Primary Antibody
Clone S18N67
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Carbamoyl Phosphate Synthetase 1
Isotype IgG1
Immunogen Recombinant protein of carbamoyl phosphate synthetase 1
Concentration 0.2 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Sodium Azide
Buffer Phosphate Buffered Saline, 0.05% BSA
Physical State Liquid

Target Information

Canine carbamoyl phosphate synthetase 1 (CPS1) is a critical enzyme in the urea cycle, catalyzing the first and rate-limiting step where it converts ammonia and bicarbonate into carbamoyl phosphate. This reaction is essential for detoxifying ammonia in dogs, as it marks the entry point of nitrogen into the urea cycle, which is the primary pathway for nitrogen disposal. CPS1 requires the cofactor N-acetyl-L-glutamate (NAG) for activation, which is synthesized from acetyl-CoA and glutamate. Deficiencies in CPS1 can lead to hyperammonemia, a condition characterized by elevated blood ammonia levels, which can result in severe neurological symptoms and even death if untreated.

Target Canine Carbamoyl Phosphate Synthetase 1
Target Synonym CPS1
Gene ID 488506
UniProt ID A0A8I3P552

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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