Mouse Anti-Canine IGF2BP2 Monoclonal Antibody

Canine IGF2BP2, or insulin-like growth factor 2 mRNA-binding protein 2, is an important regulatory protein involved in a variety of physiological functions, including embryonic development, metabolism, and the nervous system. It plays a key role in dysregulating programmed cell death, particularly in ferroptosis and autophagy, within cancer cells, and is implicated in metabolic reprogramming, especially in glucose metabolism. IGF2BP2 is known to influence the stability and translation of specific mRNAs, such as IGF2, which is associated with growth and metabolism. In dogs, IGF2BP2 may have similar functions, potentially impacting cancer progression and metabolic health, making it a significant target for therapeutic interventions and a better understanding of related diseases.