This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Anti-Canine Melanoma Cell Adhesion Molecule Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for melanoma cell adhesion molecule. It is affinity purified by protein A. It can be applied to FC assay of melanoma cell adhesion molecule.
Specifications
Target Information
Canine melanoma cell adhesion molecule (cMCAM), also known as MUC18 or Mel-CAM, is a cell surface protein found in dogs that plays a critical role in cell-cell adhesion and is particularly expressed in cells derived from melanomas, a type of cancer that originates in melanocytes. cMCAM is a transmembrane glycoprotein that is involved in homophilic adhesion, meaning it helps cells stick to other cells expressing the same molecule. This adhesion is crucial during embryonic development, wound healing, and tissue remodeling. However, the overexpression or altered expression of cMCAM has been associated with tumor progression, including increased invasiveness and metastatic potential in melanoma.
Shipping and Storage
This product is shipped with ice gel packs. Store at 2-8°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Brachelente, Chiara, et al. "Transcriptome analysis of canine cutaneous melanoma and melanocytoma reveals a modulation of genes regulating extracellular matrix metabolism and cell cycle." Scientific reports 7.1 (2017): 6386.