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Mouse Anti-Porcine Progesterone Receptor Membrane Component 2 (PGRMC2) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for progesterone receptor membrane component 2. It is affinity purified by protein A. It can be applied to WB, IHC, IF, ELISA and FC assays of progesterone receptor membrane component 2.
Specifications
Target Information
Porcine progesterone receptor membrane component 2 (pPRM2), also known as the membrane-associated progesterone receptor component 2, is an intracellular protein that plays a significant role in the rapid non-genomic signaling of progesterone, a vital hormone in reproductive physiology. This receptor is particularly important in the pig, where it contributes to the regulation of reproductive processes such as ovulation, implantation, and maintenance of pregnancy. pPRM2 is unique in its ability to mediate rapid cellular responses to progesterone, which can influence calcium signaling and other second messenger pathways. This membrane component is thought to be part of a complex signaling system that allows for the swift adaptation of the cellular environment to hormonal changes, essential for successful fertilization and early embryonic development.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Peluso, John J., et al. "Progesterone receptor membrane component (PGRMC) 1 and PGRMC2 and their roles in ovarian and endometrial cancer." Cancers 13.23 (2021): 5953.