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Mouse Anti-Porcine Progesterone Receptor Membrane Component 2 (PGRMC2) Monoclonal Antibody

Cat. No.VD8N339

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for progesterone receptor membrane component 2. It is affinity purified by protein A. It can be applied to WB, IHC, IF, ELISA and FC assays of progesterone receptor membrane component 2.

Specifications

Application WB; IF; IHC; ELISA; FC
Clonality Monoclonal
Classification Primary Antibody
Clone G7N14
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Progesterone Receptor Membrane Component 2
Isotype IgG2
Immunogen Recombinant protein of progesterone receptor membrane component 2
Purification Protein A Purified
Concentration 3300 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine progesterone receptor membrane component 2 (pPRM2), also known as the membrane-associated progesterone receptor component 2, is an intracellular protein that plays a significant role in the rapid non-genomic signaling of progesterone, a vital hormone in reproductive physiology. This receptor is particularly important in the pig, where it contributes to the regulation of reproductive processes such as ovulation, implantation, and maintenance of pregnancy. pPRM2 is unique in its ability to mediate rapid cellular responses to progesterone, which can influence calcium signaling and other second messenger pathways. This membrane component is thought to be part of a complex signaling system that allows for the swift adaptation of the cellular environment to hormonal changes, essential for successful fertilization and early embryonic development.

Target Progesterone Receptor Membrane Component 2
Target Synonym DG6; PGRMC2
Gene ID 100048965
UniProt ID A0A8W4FA00

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Peluso, John J., et al. "Progesterone receptor membrane component (PGRMC) 1 and PGRMC2 and their roles in ovarian and endometrial cancer." Cancers 13.23 (2021): 5953.
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