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Mouse Anti-Porcine Protein C Receptor (PROCR) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for protein C receptor. It is affinity purified by protein G. It can be applied to WB, IHC and ELISA assays of protein C receptor.
Specifications
Target Information
Porcine protein C receptor (pPROCR), also known as the endothelial protein C receptor (EPCR), is a membrane-bound glycoprotein that plays a critical role in the regulation of blood coagulation and inflammation. pPROCR serves as a receptor for the anticoagulant protein C, a key component of the protein C pathway, which is an important natural anticoagulant system in the blood. This receptor is highly expressed on the surface of endothelial cells, where it facilitates the activation of protein C by the thrombin-thrombomodulin complex. Once activated, protein C helps to inactivate factors Va and VIIIa, which are essential for the propagation of blood clotting, thus preventing excessive clot formation.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Fukudome, Kenji, et al. "Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor." Journal of Biological Chemistry 269.42 (1994): 26486-26491.