Mouse Anti-Porcine Ras Homolog Family Member Q (RHOQ) Monoclonal Antibody

Porcine Ras homolog family member Q (RHOQ), also known as RhoG in humans, is a small GTPase that plays a crucial role in regulating cellular functions such as migration, adhesion, and gene expression. As a target, RHOQ interacts with various cellular components to modulate these processes. It is known to control a pathway that independently activates Rac1 and Cdc42Hs, which are key regulators of actin cytoskeleton dynamics and cell migration. RHOQ has been shown to regulate the actin cytoskeleton and cell spreading through its effects on Rac1 activation. It also plays a role in cell survival by promoting the activation of PI3K and Akt, indicating its involvement in signal transduction pathways that control cell fate. Furthermore, RHOQ has been implicated in the internalization of the T cell receptor, highlighting its role in immune cell function.