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Mouse Anti-Rift Valley Fever Virus Glycoprotein C Monoclonal Antibody

Cat. No.VD7N179

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for rift valley fever virus glycoprotein C. It is affinity purified by protein A. It can be applied to SPR, WB, ELISA and FC assays of rift valley fever virus envelopment polyprotein.

Specifications

Application FACS; SPR; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone L16N7
Host Mouse
Target Species Virus
Species Reactivity Virus
Specificity Rift Valley Fever Virus Glycoprotein C
Isotype IgG2
Immunogen Purified rift valley fever virus
Purification Protein A Purified
Purity > 90%
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Proclin 300
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

The rift valley fever virus (RVFV) glycoprotein C, also known as Gn, is a key component of the virus's envelope and plays a central role in the infection process. As one of the two major surface glycoproteins of RVFV, glycoprotein C is involved in receptor binding and fusion with the host cell membrane, enabling the virus to enter and initiate infection. Glycoprotein C is a prime target for vaccine development and antiviral therapies due to its critical role in the virus's lifecycle. It is immunogenic, meaning it can elicit a strong immune response, making it a candidate for the design of subunit vaccines. Additionally, understanding the structure and function of glycoprotein C can aid in the development of monoclonal antibodies or small molecules that can inhibit its activity, thereby preventing viral entry into host cells.

Target Rift Valley Fever Virus Glycoprotein C
Target Synonym Envelopment polyprotein; M polyprotein
Taxonomy ID 11588
Gene ID 9538296
UniProt ID P03518

Shipping and Storage

This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Phoenix, Inaia, et al. "N-glycans on the Rift Valley fever virus envelope glycoproteins Gn and Gc redundantly support viral infection via DC-SIGN." Viruses 8.5 (2016): 149.
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