This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Endothelin1 (ET-1) ELISA Kit-Sandwich
Product Overview
BioVenic Rabbit Endothelin1 (ET-1) ELISA Kit-Sandwich is designed for the quantitative determination of Rabbit ET-1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Endothelin-1, encoded by the EDN1 gene in rabbits, belongs to a group of vasoconstrictor peptides derived from the endothelium. It facilitates the remodeling of the mesenteric arterial wall by activating ROCK signaling, which leads to the colocalization of NFATC3 with F-actin filaments. It has been shown that ET-1 causes significant vasoconstrictive effects in rabbits by activating endothelin A-type receptors (ETA). In a rabbit model, overexpression of ET-1 may lead to elevated blood pressure. ET-1 affects renal water-salt balance by activating ETB receptors and increasing sodium excretion. This action may be related to the mechanism of blood pressure regulation in rabbits under high salt dietary conditions.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.