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Recombinant Feline Agouti-Signaling Protein (ASIP)
Product Overview
BioVenic's Recombinant Feline Agouti-Signaling Protein (ASIP) is a recombinant protein expressed from E.coli. Its predicted molecular weight is 14.9 kDa. The purity is>85% (SDS-PAGE).
Specifications
Target Information
Feline agouti-signaling protein (ASIP) is a key regulator of coat color in cats. It interacts with the melanocortin 1 receptor (MC1R) to switch between eumelanin (black/brown pigment) and phaeomelanin (red/yellow pigment) production in hair follicles. ASIP is responsible for the agouti banding pattern seen in tabby cats, where individual hairs show alternating bands of dark and light pigments. Mutations in the ASIP gene can lead to solid-colored coats, as seen in non-agouti cats (a/a genotype), where the pigment switch is disrupted. ASIP also influences melanism (black coat color) in some cat breeds through its antagonistic effect on MC1R.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.