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Canine Cardiac Primary Fibroblasts-Immortalized by SV40T Antigens

Cat. No.CC11L846

Product TypeAnimal Cells and Cell Lines

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Product Overview

Immortalized canine cardiac primary fibroblasts are isolated from canine heart and exhibited an extended lifespan compared to normal primary cells. Primary fibroblasts are immortalized by overexpressing the large T-antigen of the simian virus 40 (SV40T antigens). Canine cardiac primary fibroblast products are utilized in various standard biochemical procedures to characterize cell products and derivatives, as well as to investigate cell-cell interactions.

Specifications

Cell Product Type Primary Cells-Immortalized
Species Canine
Cell Type Fibroblasts
Source Heart
Growth Information Adherent; 37°C; 5%CO2
Quality Control Mycoplasma (-); Bacteria (-); Yeast (-); Fungi (-)
Physical State Frozen cells or live cells in liquid culture medium

Target Information

Immortalized canine primary fibroblasts are transformed and stably express the large T-antigen of the simian virus 40 (SV40T antigens) to immortalize the cells and extend their lifespan.

Target/Biomarker SV40T antigens
Target Synonym large T antigen [ Simian virus 40 ]
Gene ID 1489531

Shipping and Storage

This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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References

  1. Liu, Dishiwen, et al. "Cardiac fibroblasts promote ferroptosis in atrial fibrillation by secreting exo-miR-23a-3p targeting SLC7A11." Oxidative Medicine and Cellular Longevity 2022 (2022).
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