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Equine Defensin (DEFb2) ELISA Kit-Sandwich

Cat. No.EK12F879

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Equine Defensin (DEFb2) ELISA Kit-Sandwich is designed for the quantitative determination of Equine Defensin (DEFb2) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Equine DEFb2.
Target Species Equine
Species Reactivity Equine
Detection Range 78.125-5000 pg/mL
Sensitivity 28 pg/mL
Recovery 80%-99%
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Defensin is encoded by the DEFb2 gene in horses. Beta-defensin 2, an antibiotic peptide, is locally regulated by inflammation. The mature defensins exhibit antimicrobial activity against a broad spectrum of microorganisms, including gram-negative and gram-positive bacteria, fungi, and enveloped viruses. Research has shown that equine β-defensins are organized similarly to other mammals and exhibit typical genomic clustering. Both DEFB2 and DEFB3 are duplicates of DEFB1.

Target/Biomarker Equine DEFb2
Target Synonym B-DF2;DEFB2;BD2;DEF-B2;HBD2;DEFB102;HBD-2;SAP1;DEFB4A;DEFB4;Skin-Antimicrobial Peptide 1
Gene ID 100629494

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Bruhn, O. et al. Antimicrobial peptides and proteins of the horse--insights into a well-armed organism. Veterinary research. 2011, 42: 98.
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