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Equine Thrombin Acivatable Fibrinolysis Inhibitor (TAFI) ELISA Kit-Sandwich

Cat. No.EK3F456

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Equine Thrombin Acivatable Fibrinolysis Inhibitor (TAFI) ELISA Kit-Sandwich is designed for the quantitative determination of Equine TAFI in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Equine TAFI.
Target Species Equine
Species Reactivity Equine
Detection Range 3.2-200 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Thrombin-activatable fibrinolysis inhibitor (TAFI) is a carboxypeptidase that cleaves C-terminal lysine residues from fibrin, which serve as binding sites for tissue plasminogen activator (tPA) and plasminogen. This action reduces fibrin's capacity to promote fibrinolysis. In horses, TAFI is encoded by the CPB2 gene. The function of TAFI in horses is mainly reflected in its regulatory effect on the fibrinolytic system, especially in diseases such as chronic glomerulonephritis. By inhibiting the production and activity of plasminogen, it reduces tissue damage and fibrosis, thereby exerting a protective effect.

Target/Biomarker Equine TAFI
Target Synonym TAFI; Thrombin Acivatable Fibrinolysis Inhibitor; Carboxypeptidase B2; CPB2
Gene ID 100058534

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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