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Mouse Anti-Chicken B-Cell Lymphoma 2 (BCL-2) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for chicken B-cell lymphoma 2. It can be applied to IF, ICC, WB and IHC assays of chicken B-cell lymphoma 2.
Specifications
Target Information
Chicken BCL-2, known as B-cell lymphoma 2 in chickens, is an anti-apoptotic protein that belongs to the BCL-2 family, which is essential in the regulation of programmed cell death, or apoptosis. This protein functions by inhibiting the release of cytochrome c from mitochondria, thereby preventing the activation of caspases, the enzymes that execute the apoptotic process. BCL-2's overexpression is associated with cell survival, while its downregulation or the imbalance with pro-apoptotic family members like Bax can lead to cell death.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Alam, Manzar, et al. "B cell lymphoma 2: a potential therapeutic target for cancer therapy." International journal of molecular sciences 22.19 (2021): 10442.